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This comforted the girl becauseanytime she was afraid at night

Humans Can Lick Too

Parents Leave Teen Daughter Home AloneHere’s how this tale (sometimes alternately titled “The Licked Hand”) goes:

A teen girl lived with her father, mother and faithful pooch in cheap moncler jackets womens a pleasant suburban neighborhood. Feeling that their daughter was finally moncler outlet sale of age (15) to look after herself while they went out for a few hours of entertainment, the parents left the daughter home alone. They instructed her to lock all the doors after their departure, and left all appropriate emergency phone numbers written down for their daughter to use if necessary.

After the parents left, the teen did some moncler online store homework then watched moncler outlet woodbury some television and had a rather ordinary evening. Later into the moncler outlet evening, however, even though her parents hadn’t returned home yet, she faced a small dilemma: appear confident and capable to her parents and just go to bed or else watch and wait up for her parents to arrive back home. Although the teen was a bit nervous about being alone, she didn’t want her parents to find this out and, perhaps, not trust her to be on her own again. She decided to go to bed and not wait up for them. After all, she really wasn’t TOTALLY alone. Her dog was with her and this was comforting to her.

Off she went to bed, her pooch settling beside the bed, laying on the floor moncler moncler outlet usa as he usually did each night. Nervous or not, it wasn’t long best moncler jackets until the teen fell asleep.

The teen stirred from slumber briefly, hearing a noise sort of like monclerdownjacket a dripping faucet from down the hall. It was slightly annoying but of little concern to the sleepy teen. It probably meant that her parents had returned home and had used the bathroom faucet recently, that’s all. She reached a hand down beside her bed and the dog comforted her by licking her hand, so she put any worries about the noise aside and allowed herself to fall back asleep.

Pretty soon, the teen stirred again, hearing the dripping sound uk moncler sale some more. Affected by a strain of apprehension, she wondered why her parents hadn’t stopped up the faucet yet. She reached down her cheap moncler jackets mens hand and felt the dog lick her hand again, but really was getting too warm moncler uk outlet and comfortable under her blankets to think more on the matter. Besides, her pooch was beside her for protection. She went back to sleep.

The teen awakened a moncler sale outlet third time, still noting a dripping noise nearby. Annoyed this time, she looked across to her alarm moncler outlet store clock on the bedside table. The time glowed from the table: 3:30am. She decided to go tighten the faucet herself in order to finally get some uninterrupted uk moncler outlet sleep. She noted that her dog moncler sale online wasn’t beside the bed when she swung her legs down from the bed.

As she walked to the cheap moncler coats mens bathroom, the dripping moncler outlet prices noise sounded more clear, so she was glad she decided to just get up and fix this problem. She was so overwhelmed that she gagged instead of screaming. She turned to run away but was stopped in her tracks when she moncler outlet online glanced at the mirror.

Written in big letters, from the dog’s blood:

The ‘kitchen’ VersionA little girl had a dog that slept under her bed every night. This comforted the girl becauseanytime she was afraid at night, she would reach her hand under the bed and thus, know that she was not alone when her dog would lick her hand. This measure of comfort would allow her tofeel safe and fall easily cheap moncler jackets and quickly back to sleep.

One night, the girl went to sleep but was awakened in the middle of the night by a strange noise. She lay awake listening, but heard nothing further that was of concern. Shecould clearly hear a familiar sound that of a dog panting, so she assumed that, perhaps, her moncler womens jackets dog had just recently bumped intosomething in the night,causing the noise that had awakened her before returningto lay under her bed. She reached her hand down and under the bed. In a few seconds, she felt the moncler sale dog lick her hand, so she was comforted and fell back to sleep.

Some time later, the girl woke up again. This time, it was because she was hungry. She got out of bed and went to the kitchen, and as she entered the kitchen, she stopped because she heard a noise.

But the faucet wasn’t dripping at all.

When she peered into the sink basin, she saw a bloodied butcher knife and thought it strange that her parents hadn’t at least rinsed something like that off and discount moncler jackets put it back away properly. She felt suddenly frightened by the sight and also became aware of the dripping noise again. In her anxiety, she backed up against the fridge, scanningthepoorly moonlight room with eyes darting nervously. All the while, she continued to hear, “Drip, drip, drip, drip.”

Finally, she spun and opened the fridge door to shed some light on the situation.

There, hanging inside the fridge was her pet dog, freshly butchered.

Alternate VersionsThis urban legend is also called “Doggy Lick,” “Humans Lick Too,” “Licked Hand,” “People Lick, Too,” “The Licked Hand,” and similar variations and word combinations referring to “lick,” “hand,” “humans,” and “people.”

Along with slightly different titles, there are slight variations in details which make this urban legend very interesting. Below are possibilities for this urban legend.

the person who is home alone is a teenager

the person who is home alone is an elderly person

the person who is home is in her early 20’s (for the US, this is still considered “youth” and age of minority in most states, so the persona is still at a “risky” age)

I have not yet come across a version of this urban legend where the person home alone is male

I have not yet come across a version of this urban legend where the age of the person home alone is under teenage years however there’s a “home alone” urban legend with two siblings, one of which is pre teen, called, “Knock Knock Knock” and it’s pretty scaryDetails About The Dog:

the cheap moncler sale dog gets locked in the basement and is unharmed the girl has been trying to sleep and hears noises from outside her room, somewhere in the house. She puts her hand by the side of the bed and her hand is licked. This repeats several times until the noises she hears are a bit louder. creepy.

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canada goose coats uk Among scientists, Doudna is known for her painstaking attention to detail, which she often harnesses to solve problems that other researchers have dismissed as intractable. Charpentier, who is French but works in Sweden and Germany, is livelier and more excitable. But as the pair began discussing the details of the experiment, they quickly hit it off. ”I really liked Emmanuelle,” Doudna says. ”I liked her intensity. I can get that way, too, when I’m really focused on a problem. It made me feel that she was a like minded person.” canada goose coats uk

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canada goose parka outlet The other thing that made Crispr Cas9 tantalizing was its ability to direct its protein, Cas9, to precisely snip out a piece of DNA at any point within canada goose the genome and then neatly stitch the ends back together. Such effortless editing had a deep appeal: In the lab, the process remained cumbersome. At the canada goose black friday sale time, though, Doudna didn’t think much about Crispr’s potential as a gene editing tool. Researchers had stumbled on such systems in the past, but struggled to harness them. Nonetheless, she says: ”I had this feeling. You know when you pick up a canadian goose jacket suspense novel, and read the first chapter, and you get a little chill, and you know, ‘Oh, this is going to be good’? It was like that.” canada goose parka outlet

canada goose outlet in vancouver Doudna arranged for a postdoctoral researcher, Martin Jinek, to collaborate with Charpentier’s team. After months of experimentation, they determined that Crispr relied on two separate kinds of RNA: canada goose clearance a guide, which targeted the Cas9 protein to a particular location, and a tracer, which enabled the protein to cut the DNA. But even then, it wasn’t clear whether Crispr was anything more than a curiosity. Unlike most living things people, animals, plants the cells of bacteria have no nucleus, and their RNA and DNA interact in a different way. Because of that, Jinek says, canada goose uk shop it was hard to say ”whether the system would be portable” whether it would work in anything except bacteria. Going over the problem in Doudna’s office, Jinek began sketching the two RNA molecules on the whiteboard. In their natural form, Canada Goose Outlet the two are separate, but Doudna and Canada Goose Coats On Sale Jinek believed that it would be possible to combine them into a single tool one that was more likely to work in a wide range of organisms. ”That was the moment the project went from being ‘This is cool, this is wonky’ to ‘Whoa, this could be transformative,”’ Doudna says. canada goose outlet in vancouver

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canada goose outlet phone number The tool Doudna ultimately created with her collaborators paired Crispr’s programmable guide RNA with a shortened tracer RNA. Used in combination, the system allowed researchers to target and excise any gene they wanted or even edit out a single base pair within a gene. (When researchers want to add a gene, they can use Crispr to stitch it between the two cut ends.) Some researchers have compared Crispr to a word processor, capable of effortlessly editing a gene down to the level of a single letter. canada goose outlet phone number

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canada goose outlet niagara falls In the era of Crispr (short for Clustered Regularly Interspaced Short Palindromic Repeats, a reference to the gene’s structure), those limitations are already disappearing. In October, Harvard researchers used Crispr to simultaneously alter 62 genes in pig embryos, creating animals that could, at least in theory, grow human organs for transplant. Uncannily, the tool also seemed to work in nearly every organism, from silkworms to monkeys, and also in every cell type: kidney, heart and those, like T cells, that researchers had previously struggled to modify. In early November, the biotechnology start up Editas Medicine announced that it planned to test a Crispr based gene therapy technique in hopes of curing a rare form of blindness, by deleting part of a gene that controls the eye’s photoreceptor cells. But most researchers believe that Crispr’s biggest impact will be in speeding up the drug pipeline. Drug development currently relies, in part, on genome wide association studies to identify mutations that people with a canada goose factory sale certain disease have in common. The problem is that those studies typically turn up hundreds of loosely associated mutations, each of which may or may not actually relate to the disease. (Some of them may be caused by the disease.) Before Crispr, it was so difficult to edit a single gene accurately that researchers had no easy way to test which mutations actually mattered, and thus which ones to target when looking for a cure. canada goose outlet niagara falls

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canada goose outlet uk Doudna’s interest in science developed early. In the 1970s, her father, Martin, got a job teaching literature at the University of Hawaii, and the family settled in Hilo. At the time, Hilo had what a former schoolmate, Lisa Twigg Smith, described as ”a sugar plantation culture” multiethnic, blue collar, tough and Doudna, with her blond hair and earnest interest in school, stood out. ”I was kind of a nerdy, geeky type,” Doudna says. ”And I loved math. People teased me about it. I felt pretty much like an outcast.” canada goose outlet uk

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canada goose outlet eu In sixth grade, Doudna began spending time with Twigg Smith. Both girls lived in a tract home development where, Twigg Smith says, ”every third house was the same.” The development was new, but it was built into wild countryside; after school, Lisa would ride her bicycle over to Jennifer’s house, canada goose coats and the girls would head up the cane road, buy canada goose jacket cheap an overgrown track that led to a nearby sugar cane field. The landscape was rugged and lush, a plane of steep lava rock overgrown with ferns and cut with flooded meadows where the grass grew in clumps. canada goose outlet eu

canada goose factory outlet vancouver ”We spent a lot of time walking and looking, just talking about whatever was the topic of the day,” Twigg Smith says. ”We’d follow wild pig trails, or else we’d just look at things at mosses that were in bloom, or mushrooms.” While on these walks, Doudna became interested in a species of mimosa known locally as hila hila, or sleeping grass. The plant’s runners were thorny and tough, but its leaves were unexpectedly delicate and folded shut if touched. Doudna recalls being fascinated not by the plant, but by the mechanism that drove it. ”I’d look at that and think: Now, how does that work? There’s some chemical change that responds to touch, that allows these leaves to close. But what is it? I couldn’t imagine.” canada goose factory outlet vancouver

canada goose outlet new york city She was encouraged by a family friend, Don Hemmes, a biologist who specialized in fungi. She spent a summer working in his lab, collecting samples and embedding them in resins, then examining thin slices under an electron microscope. Though many teenagers would have found the work tedious, Doudna was captivated by it. ”I looked forward to going in every day,” she says. ”I would get this feeling a sort of excitement. Like, ‘I’m going to uncover a mystery today!”’ canada goose outlet new york city

canada goose outlet in canada From the start, Doudna told me, she has been drawn not to the larger forces in the natural world but to the hidden, microscopic mechanisms that drive it: the molecular chain that magically makes the hila hila close. But in many ways Canada Goose sale she was an unlikely genetics pioneer. Before developing Crispr, Doudna had little experience editing genes and had never worked in human or animal Canada Goose online research. And while she was well known in her field, her work which focused on the structure and function of various kinds of RNA was considered abstruse, even by science standards. ”It’s a pretty rarefied interest,” one scientist told me. ”To be good at it, you have to be very patient and meticulous.” canada goose outlet in canada

canada goose outlet canada At the time Doudna began studying Canada Goose Outlet RNA, in graduate school, the molecule was thought of primarily as a go between: When a coil of DNA unzipped, the RNA would copy the orders encoded by a given gene, then ferry those instructions over to the cell’s protein making machinery, which would use them as a blueprint for snapping together amino acids. But even as public attention (and research grants) focused on familiar problems like sequencing genes, the future was quietly arriving from another direction. To everyone’s surprise, RNA turned out to be both more diverse and more powerful than researchers imagined: Thousands of varieties have been identified, some with the power to turn genes on or off, or to disable invaders by Canada Goose Parka jamming their genetic machinery. While DNA is a library containing all our genes, in other words, RNA is more like a fleet of dynamic librarians, constantly cataloging and patrolling the stacks. canada goose outlet canada

canada goose outlet uk sale Doudna made her name as a postdoctoral researcher by mapping the structure of a particular type of RNA known as a ribozyme: a molecule able to catalyze chemical reactions by twisting to bring different atoms in contact with one another. Researchers typically figure out how something like a ribozyme functions by laboriously tracing the individual interactions among atoms a process that Tom Cech, who was Doudna’s postdoctoral adviser, likened to mapping a forest at night canada goose uk black friday by feeling your way from tree to tree canada goose outlet uk sale.